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Phenacetin was used as an analgesic and fever-reducing drug in both human and veterinary medicine for many years. It was introduced into therapy in 1887 and was extensively used in analgesic mixtures until it was implicated in kidney disease (nephropathy) due to abuse of analgesics.
What is another name for phenacetin?
Phenacetin (acetophenetidin, N-(4-ethoxyphenyl)acetamide) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887。
Is paracetamol a phenacetin?
difference between the drugs there is also much clinical data to confirm that phenacetin and paracetamol are different. Analgesic/Antipyretic Brodie & Axelrod in 1949 when demon- strating the formation of paracetamol from phenacetin suggested that the analgesic activity of phenacetin was directed through paracetamol.
What class of drug is phenacetin?
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Phenacetin is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group. It has a role as a non-narcotic analgesic, a peripheral nervous system drug and a cyclooxygenase 3 inhibitor.